Structure of PDB 7phr Chain A

Receptor sequence

>7phrA (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]

PQALSIQEGENATMNCSYKTSINNLQWYRQNSGRGLVHLILIRSNEREKH
SGRLRVTLDTSKKSSSLLITASRAADTASYFCATDGSTPMQFGKGTRLSV
IPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKT
VLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESSCDVK
LVEKSFETDTNLNFQNLSVIGFRILLLKVAGFNLLMTLRLWSS

3D structure

PDB

7phr Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC.

Chain

Resolution

3.08 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	N31 T96	N23 T88
BS02	peptide	A	V227 R231 L246 W249	V219 R223 L238 W241

External links

PDB	RCSB:7phr, PDBe:7phr, PDBj:7phr
PDBsum	7phr
PubMed	35985289

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