Structure of PDB 7pdq Chain A

Receptor sequence
>7pdqA (length=208) Species: 10090 (Mus musculus) [Search protein sequence]
DMPVEKILEAELADPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVI
LLRAGWNELLIASFSHESIAVKDGILLATGLHVHRNSAHSAGVGAIFDRV
LTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYAS
LEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKQLEHLFFFKLIGDTPIDT
FLMEMLEA
3D structure
PDB7pdq Design and in vitro characterization of RXR variants as tools to investigate the biological role of endogenous rexinoids.
ChainA
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F282 V285 K289 V303 R307 T454 E458 F28 V31 K35 V49 R53 T200 E204
BS02 LG2 A I273 A277 L314 F318 L331 A332 Q437 F444 I19 A23 L60 F64 L77 A78 Q183 F190
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pdq, PDBe:7pdq, PDBj:7pdq
PDBsum7pdq
PubMed35900852
UniProtP28700|RXRA_MOUSE Retinoic acid receptor RXR-alpha (Gene Name=Rxra)

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