Structure of PDB 7p9o Chain A

Receptor sequence
>7p9oA (length=274) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
LSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAGAGRYQLG
STGKYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPLIARQ
LLREQDSLQLTELHPSDYPLLRSEFQKDSRARVEKADGFQQLKAKLPPVS
RRGLILIDPPYEMKTDYQAVVSGIAEGYKRFATGTYALWYPVVLRQQIKR
MIHDLEATGIRKILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNNV
LPWLHSKLVPAGTGHATVSWIVPE
3D structure
PDB7p9o Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase.
ChainA
Resolution2.095 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.266: 23S rRNA (adenine(2030)-N(6))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0Y0 A K18 H19 H42 A43 S100 E118 L119 A142 D143 G144 D164 K17 H18 H41 A42 S94 E112 L113 A136 D137 G138 D158
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008649 rRNA methyltransferase activity
GO:0008988 rRNA (adenine-N6-)-methyltransferase activity
GO:0036307 23S rRNA (adenine(2030)-N(6))-methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0015976 carbon utilization
GO:0032259 methylation
GO:0070475 rRNA base methylation
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:7p9o, PDBe:7p9o, PDBj:7p9o
PDBsum7p9o
PubMed35580049
UniProtP37634|RLMJ_ECOLI Ribosomal RNA large subunit methyltransferase J (Gene Name=rlmJ)

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