Structure of PDB 7p8q Chain A

Receptor sequence
>7p8qA (length=275) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
LSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAGAGRYQLG
SETGEYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPLIAR
QLLREQDSLQLTELHPSDYPLLRSEFQKDSRARVEKADGFQQLKAKLPPV
SRRGLILIDPPYEMKTDYQAVVSGIAEGYKRFATGTYALWYPVVLRQQIK
RMIHDLEATGIRKILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNN
VLPWLHSKLVPAGTGHATVSWIVPE
3D structure
PDB7p8q Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase.
ChainA
Resolution2.289 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.266: 23S rRNA (adenine(2030)-N(6))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A H9 N12 K18 E60 Y167 E168 Y173 W195 V199 H8 N11 K17 E55 Y162 E163 Y168 W190 V194
BS02 6D6 A H42 A43 S100 E118 L119 D143 D164 P165 W195 H41 A42 S95 E113 L114 D138 D159 P160 W190
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008649 rRNA methyltransferase activity
GO:0008988 rRNA (adenine-N6-)-methyltransferase activity
GO:0036307 23S rRNA (adenine(2030)-N(6))-methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0015976 carbon utilization
GO:0032259 methylation
GO:0070475 rRNA base methylation
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7p8q, PDBe:7p8q, PDBj:7p8q
PDBsum7p8q
PubMed35580049
UniProtP37634|RLMJ_ECOLI Ribosomal RNA large subunit methyltransferase J (Gene Name=rlmJ)

[Back to BioLiP]