Structure of PDB 7p4b Chain A

Receptor sequence
>7p4bA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRWKP
3D structure
PDB7p4b Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
ChainA
Resolution1.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 H9 R62 E63 S66 N77 Y84 W97 S143 K146 E152 Q156 Y159 W167 Y171 Y7 H9 R62 E63 S66 N77 Y84 W97 S143 K146 E152 Q156 Y159 W167 Y171
BS02 peptide A I73 A150 E152 H155 I73 A150 E152 H155
External links
PDB RCSB:7p4b, PDBe:7p4b, PDBj:7p4b
PDBsum7p4b
PubMed35705051
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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