Structure of PDB 7p2d Chain A

Receptor sequence
>7p2dA (length=751) Species: 9606 (Homo sapiens) [Search protein sequence]
FNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQC
DYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSEN
TYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDF
RRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVK
PITQLLGRTHTATGIRKVVRELFRITNGARKNAFKILVVITDGEKFGDPL
GYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVN
NFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLL
STVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRV
QSLVLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDV
DSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQ
PWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISP
SHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQ
PVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRL
REGQIQSVVTYDLALDSGRPHSRAVFNETKRSTRRQTQVLGLTQTCETLK
LQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFP
F
3D structure
PDB7p2d Structural insights into the function-modulating effects of nanobody binding to the integrin receptor alpha M beta 2.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D514 N516 D518 L520 D522 D514 N516 D518 L520 D522
BS02 CA A T579 D581 L583 D585 T579 D581 L583 D585
Gene Ontology
Cellular Component
GO:0008305 integrin complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7p2d, PDBe:7p2d, PDBj:7p2d
PDBsum7p2d
PubMed35738398
UniProtP11215|ITAM_HUMAN Integrin alpha-M (Gene Name=ITGAM)

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