Structure of PDB 7p1e Chain A

Receptor sequence
>7p1eA (length=383) Species: 341663 (Aspergillus terreus NIH2624) [Search protein sequence]
DPAKDATPYHVEFPLFRSANMASADKLSTGVGFHSFRIPAVVRTTTGRIL
AFAEGRRHDNRDFGDINLVYKRTKTTSDNGATLSDWESLREVVGSGDGTW
GNPTPVVDcGTIYLFLSWNNGSYSQKGGDELPDGTITKKIDTTWYGRRHL
YLTTSTDDGNTWSKPQDLTKELTPDGWSWDAVGPGNGIKLSSGELVVPAM
GRNIVGRGTPGQRTWSVQRLNGAGAEGTVCETPDGKLYRNDRPSKAGYRI
VARGTLSDGFSDFASDSGLPDPACQGSVLKYNTDAPPRTIFLNSASSDSR
RQMRVRISYDADAAKYDYGRKLADAPVSGAGYEGGYSSMTKTADYKIGAL
VESDFFNDGTGGGSYRSIIWRRFNLSWILNGPN
3D structure
PDB7p1e Kinetic and Structural Characterization of Sialidases (Kdnases) from Ascomycete Fungal Pathogens.
ChainA
Resolution1.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FKD A R56 I57 D81 Q144 E245 R261 R319 Y355 R37 I38 D62 Q125 E226 R242 R300 Y336
BS02 K99 A D84 N86 E110 G113 S114 G115 D65 N67 E91 G94 S95 G96
BS03 CA A D84 N86 G113 G115 D65 N67 G94 G96
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006689 ganglioside catabolic process
GO:0009313 oligosaccharide catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7p1e, PDBe:7p1e, PDBj:7p1e
PDBsum7p1e
PubMed34724608
UniProtQ0CMX0

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