Structure of PDB 7ovs Chain A

Receptor sequence
>7ovsA (length=382) Species: 10090 (Mus musculus) [Search protein sequence]
PKLSLIKVVNGCRLGKIQNLGKAGDCTVDIPGCLLYTRTGSAPHLTHQTL
RNIHGVPGIAQLTLSSLAEHHEVLAEYKKGVGSFIGMPESLFYCSLHDPV
TPGPAGYVTSKSVSVWGFGGRVEMTVSKFMAIQEALQPDWFQCLSDGEAS
CAETTSIKRARKSVDRSLLFLDSCLRLQEESEVLQKSVIIGVIEGGDVME
ERLRSARETAKRPVGGFLLDGFQGDPAVTETRLHLLSSVTAELPEDKPRL
ICGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFTFDCQLEMTSFE
INLKEKKYQEDFDPLVRGCSCYCCKNHTRAYIHHLLMTNELLAGVLLMMH
NFEHYFGFFCSIREALKNDTLAQLKELICRQM
3D structure
PDB7ovs Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.29: tRNA-guanosine(34) preQ1 transglycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C351 C353 C356 H382 C319 C321 C324 H350
BS02 TEW A T109 S110 K111 K162 R166 T109 S110 K111 K162 R166
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008479 tRNA-guanosine(34) queuine transglycosylase activity
GO:0016763 pentosyltransferase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0101030 tRNA-guanine transglycosylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0032473 cytoplasmic side of mitochondrial outer membrane
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ovs, PDBe:7ovs, PDBj:7ovs
PDBsum7ovs
PubMed35815944
UniProtB8ZXI1|QTRT2_MOUSE Queuine tRNA-ribosyltransferase accessory subunit 2 (Gene Name=Qtrt2)

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