Structure of PDB 7oot Chain A

Receptor sequence
>7ootA (length=111) Species: 9606 (Homo sapiens) [Search protein sequence]
GKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAALF
KAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDP
YKVYRIVPEGA
3D structure
PDB7oot X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to interferon-stimulated response element
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A W54 H56 A57 P91 K94 R98 N102 K103 W33 H35 A36 P70 K73 R77 N81 K82
BS02 dna A G22 L24 G58 K59 Q60 W74 K78 K80 R96 K103 G1 L3 G37 K38 Q39 W53 K57 K59 R75 K82
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7oot, PDBe:7oot, PDBj:7oot
PDBsum7oot
PubMed
UniProtQ15306|IRF4_HUMAN Interferon regulatory factor 4 (Gene Name=IRF4)

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