Structure of PDB 7onk Chain A

Receptor sequence
>7onkA (length=512) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
GDARSVRHIAIPAHRGLITDRNGEPLAVSTPVTTLWANPKELMTAKERWP
QLAAALGQDTKLFADRIEQNAEREFIYLVRGLTPEQGEGVIALKVPGVYS
IEEFRRFYPAGEVVAHAVGFTDVDDRGREGIELAFDEWLAGVPGKRQVLK
DRRGRVIKDVQVTKNAKPGKTLALSIDLRLQYLAHRELRNALLENGAKAG
SLVIMDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVK
PFSMSAALASGRWKPSDIVDVYPGTLQIGRYTIRDVSRNSRQLDLTGILI
KSSNVGISKIAFDIGAESIYSVMQQVGLGQDTGLGFPGERVGNLPNHRKW
PKAETATLAYGYGLSVTAIQLAHAYAALANDGKSVPLSMTRVDRVPDGVQ
VISPEVASTVQGMLQQVVEAQGGVFRAQVPGYHAAGKSGTARKVSVENAY
RSLFAGFAPATDPRIAMVVVIDEPSKYFGGLVSAPVFSKVMAGALRLMNV
PPDNLPTAKLVP
3D structure
PDB7onk Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria.
ChainA
Resolution1.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.16.4: serine-type D-Ala-D-Ala carboxypeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VL5 A E291 S294 V333 S349 Y409 S485 G486 T487 A488 R489 Y532 F533 E244 S247 V286 S302 Y362 S438 G439 T440 A441 R442 Y477 F478
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0008658 penicillin binding
GO:0008955 peptidoglycan glycosyltransferase activity
GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
Biological Process
GO:0000917 division septum assembly
GO:0006508 proteolysis
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0043093 FtsZ-dependent cytokinesis
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7onk, PDBe:7onk, PDBj:7onk
PDBsum7onk
PubMed34356681
UniProtG3XD46|FTSI_PSEAE Peptidoglycan D,D-transpeptidase FtsI (Gene Name=ftsI)

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