Structure of PDB 7om7 Chain A

Receptor sequence

>7om7A (length=628) Species: 83810 (Thosea asigna virus) [Search protein sequence]

TRLSLEAMLAERAMVARQDLAGLKRKLAGADRVLAPQSPEQCGRESAQAQ
ARSVTSELKSAVKEAQGLEHQTLDFLEQLGEYPVCGILHGDHPVHPSGTH
NNNGKVSVKRQFAASDALTCAFRFEDSDLVRETALKTTYTDGTWAGFVQR
LKMQTTRKCVQEKVSRKLLKQLFPYDPQKLVDVSGELSELVLGIKTNAIA
SAGPPYWRTKRDALPDMLDCVLPLLYDHIVRKDLTTLRNKHPELFLAECK
NKTDRYEVESLGEKTRPYFSHPFHLSALVSVLSQSFSGALKIMTEDSTSF
NAYGFSWTNGGAEDLAIWARQAGEAGKKPPRIACYGDDTDIYYRKDGKLY
RICPDFKQMDGSVDATTIEAVVDYVVDAHVKQYPTARQFWEEVGKLWVEM
ATQSPFLIDGTKVYRKMQKDGLMTGVVGTTLFDTVKSALAYNDWADQLMF
GSLNLLEEKYAIEFFKNKHGLVIKEGTWKPALVNEDPGFGELWTEQKFLG
LQLKVVRRENEKVYVPNLPFEDWLTMWVTPRSTETMRERTLFDRARGLLV
TGAVFDERARGLMGAVINSTAPEVVCMRVQISDGYPSYDWVVSLYSRDHP
CDMPRVFPEAATLIASYRKQVMDTRVVI

3D structure

PDB

7om7 Snapshots of a Non-Canonical RdRP in Action.

Chain

Resolution

2.4 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	A	R269 Y349 D351 L513 M540 R545 D563 R564 G567 L568 T571 Q600	R255 Y335 D337 L499 M526 R531 D543 R544 G547 L548 T551 Q580
BS02	rna	A	Y153 N211 A214 S215 K224 K264 Y282 S284 S294 Q298 Y317 G318 S320 G439 V441 W633	Y139 N197 A200 S201 K210 K250 Y268 S270 S280 Q284 Y303 G304 S306 G425 V427 W590
BS03	2KH	A	K266 R280 Q372 D374 T438 T443 D447 K488	K252 R266 Q358 D360 T424 T429 D433 K474

External links

PDB	RCSB:7om7, PDBe:7om7, PDBj:7om7
PDBsum	7om7
PubMed	34203380
UniProt	Q6A562

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