Structure of PDB 7om6 Chain A

Receptor sequence

>7om6A (length=630) Species: 83810 (Thosea asigna virus) [Search protein sequence]

TRLSLEAMLAERAMVARQDLAGLKRKLAGADRVLAPQSPEQCGRESAQAQ
ARSVTSELKSAVKEAQGLEHQTLDFLEQLGEYPVCGILHGDHPVHPSGTH
NNNGKVSVKRQFAAGVSDALTCAFRFEDSDLVRETALKTTYTDGTWAGFV
QRLKMQTTRKCVQEKVSRKLLKQLFPYDPQKLVDVSGELSELVLGIKTNA
IASAGPPYWRTKRDALPDMLDCVLPLLYDHIVRKDLTTLRNKHPELFLAE
CKNKTDRYEVESLGEKTRPYFSHPFHLSALVSVLSQSFSGALKIMTEDST
SFNAYGFSWTNGGAEDLAIWARQAGEAGKKPPRIACYGDDTDIYYRKDGK
LYRICPDFKQMDGSVDATTIEAVVDYVVDAHVKQYPTARQFWEEVGKLWV
EMATQSPFLIDGTKVYRKMQKDGLMTGVVGTTLFDTVKSALAYNDWADQL
MFGSLNLLEEKYAIEFFKNKHGLVIKEGTWKPALVNEDPGFGELWTEQKF
LGLQLKVVRRENEKVYVPNLPFEDWLTMWVTPRSTETMRERTLFDRARGL
LVTGAVFDERARGLMGAVINSTAPEVVCMRVQEISDGYPSYDWVVSLYSR
DHPCDMPRVFPEAATLIASYRKQVMDTRVV

3D structure

PDB

7om6 Snapshots of a Non-Canonical RdRP in Action.

Chain

Resolution

2.18 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	A	R269 Y349 G350 D351 L513 M540 R545 D563 R564 G567 L568 T571 Q600 E601	R257 Y337 G338 D339 L501 M528 R533 D545 R546 G549 L550 T553 Q582 E583
BS02	rna	A	A214 S215 K224 K264 Y282 F283 S284 S294 Y317 G318 S320 T322 Y349 G439 V441	A202 S203 K212 K252 Y270 F271 S272 S282 Y305 G306 S308 T310 Y337 G427 V429

External links

PDB	RCSB:7om6, PDBe:7om6, PDBj:7om6
PDBsum	7om6
PubMed	34203380
UniProt	Q6A562

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