Structure of PDB 7om3 Chain A

Receptor sequence

>7om3A (length=759) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence]

MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEE
VKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKI
REHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFAIATLYHEGE
EFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKE
KDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAV
EVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWE
TGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTG
NLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENI
VYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIP
SLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRAIKILANSYYGYYGYA
RARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPG
ADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEE
GKITTRGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKL
SKYEVPPEKLVIHEQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVIS
YIVLKGSGRIGDRAIPFDEFDPTKHKYDAEYYIENQVLPAVERILRAFGY
RKEDLRYQK

3D structure

PDB

7om3 Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase.

Chain

Resolution

1.92 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	Y7 P36 Y37 R58 H59 H89 P90 Q91 V93 P94 R97 Y112 D113 I114 P115 F116 K118 R119 K240 G245 R247 D343 S348 T349 N351 K371 S383 Y384 G386 G387 V389 S492 G495 Y496 G498 Y499 R501 T590 K591 K593 W615 P678 R709 I710 G711 Y731 R743	Y7 P36 Y37 R58 H59 H89 P90 Q91 V93 P94 R97 Y112 D113 I114 P115 F116 K118 R119 K240 G245 R247 D343 S348 T349 N351 K371 S383 Y384 G386 G387 V389 S492 G495 Y496 G498 Y499 R501 T590 K591 K593 W615 P678 R709 I710 G711 Y731 R743
BS02	dna	A	N269 D540 K592 Y594 R606 G607 V611 R612 R613 Q665 T667 R668 Y673 K674 H679	N269 D540 K592 Y594 R606 G607 V611 R612 R613 Q665 T667 R668 Y673 K674 H679

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003887	DNA-directed DNA polymerase activity

View graph for
Molecular Function

External links

PDB	RCSB:7om3, PDBe:7om3, PDBj:7om3
PDBsum	7om3
PubMed	34486208
UniProt	P77933\|DPOL_THEKO DNA polymerase (Gene Name=pol)

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