Structure of PDB 7ohi Chain A

Receptor sequence
>7ohiA (length=250) Species: 10090 (Mus musculus) [Search protein sequence]
GSPGILAPLAPGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMF
IFYGNKTSTQFLNFTPTLICADDLQTNLNLQTKPVKPTVDGGAQVQQVVN
IECISDFTEAPVLNIQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQ
RWKQLSNPQQEVQNIFKAKHPMDTEITKAKIIGFGSALLEEVDPNPANFV
GAGIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKDTVSQRLCELLSEQF
3D structure
PDB7ohi FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
ChainA
Resolution1.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F837 W840 I853 D881 R905 E907 N909 Y915 R916 F149 W152 I165 D193 R217 E219 N221 Y227 R228
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030117 membrane coat
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7ohi, PDBe:7ohi, PDBj:7ohi
PDBsum7ohi
PubMed35486718
UniProtP17427|AP2A2_MOUSE AP-2 complex subunit alpha-2 (Gene Name=Ap2a2)

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