Structure of PDB 7oc8 Chain A

Receptor sequence
>7oc8A (length=434) Species: 51453 (Trichoderma reesei) [Search protein sequence]
QSACTLQSETHPPLTWQKCSSGGTCTQQTGSVVIDANWRWTHATNSSTNC
YDGNTWSSTLCPDNETCAKNCCLDGAAYASTYGVTTSGNSLSIDFVTQSA
QKNVGARLYLMASDTTYQEFTLLGNEFSFDVDVSQLPCGLNGALYFVSMD
ADGGVSKYPTNTAGAKYGTGYCDSQCPRDLKFINGQANVEGWEPSSNNAN
TGIGGHGSCCSQMDIWEANSISEALTPHPCTTVGQEICEGDGCGGTYSDN
RYGGTCDPDGCDWNPYRLGNTSFYGPGSSFTLDTTKKLTVVTQFETSGAI
NRYYVQNGVTFQQPNAELGSYSGNELNDDYCTAEEAEFGGSSFSDKGGLT
QFKKATSGGMVLVMSLWDDYYANMLWLDSTYPTNETSSTPGAVRGSCSTS
SGVPAQVESQSPNAKVTFSNIKFGPIGSTGNPSG
3D structure
PDB7oc8 Enzyme kinetics by GH7 cellobiohydrolases on chromogenic substrates is dictated by non-productive binding: insights from crystal structures and MD simulation.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.91: cellulose 1,4-beta-cellobiosidase (non-reducing end).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A R251 Y381 R394 R251 Y381 R394
BS02 GAL A Q175 E217 H228 D259 W376 Q175 E217 H228 D259 W376
BS03 NPO A N307 G308 N307 G308
BS04 NPO A G339 Y381 G339 Y381
BS05 CO A H206 E239 H206 E239
BS06 CO A E295 E325 E295 E325
BS07 CO A D214 E217 H228 D214 E217 H228
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7oc8, PDBe:7oc8, PDBj:7oc8
PDBsum7oc8
PubMed35997626
UniProtP62694|GUX1_HYPJE Exoglucanase 1 (Gene Name=cbh1)

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