Structure of PDB 7o6c Chain A

Receptor sequence
>7o6cA (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
GPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSR
YFLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWESGLHAMECA
LLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHVH
NLVKMGAPDAGLAEYLFDTHTLG
3D structure
PDB7o6c Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FE2 A E27 E62 H65 E24 E59 H62
BS02 FE2 A E62 E107 Q141 E59 E104 Q138
BS03 FE2 A Q58 E61 Q55 E58
BS04 FE2 A E140 S144 E137 S141
BS05 FE2 A H57 E61 H54 E58
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7o6c, PDBe:7o6c, PDBj:7o6c
PDBsum7o6c
PubMed34343376
UniProtQ8N4E7|FTMT_HUMAN Ferritin, mitochondrial (Gene Name=FTMT)

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