Structure of PDB 7o6a Chain A

Receptor sequence
>7o6aA (length=172) Species: 9606 (Homo sapiens) [Search protein sequence]
PSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSRY
FLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWESGLHAMECAL
LLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHN
LVKMGAPDAGLAEYLFDTHTLG
3D structure
PDB7o6a Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FE2 A E27 E62 H65 E23 E58 H61
BS02 FE2 A E62 E107 Q141 E58 E103 Q137
BS03 FE2 A Q58 E61 Q54 E57
BS04 FE2 A H57 E61 H53 E57
BS05 FE2 A E140 S144 E136 S140
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7o6a, PDBe:7o6a, PDBj:7o6a
PDBsum7o6a
PubMed34343376
UniProtQ8N4E7|FTMT_HUMAN Ferritin, mitochondrial (Gene Name=FTMT)

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