Structure of PDB 7o4o Chain A

Receptor sequence
>7o4oA (length=226) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
GMISLNNRLTTVSRFLKQGTIADIGSDHAYLPIYAIQNHLCECGIAGEVI
QGPFQAAVKNVAANQLVDRIDVRLGDGLSVIQPEDVIDNITICGMGGPLI
AKILKDGQDKLSQHPRLILQSNIQTENLRQTLQQLNYEIIDEIIMEEKGH
IYEIVVAEYSTELIELSSDELKFGPKLLNNKNEYFIKKWQRELEALYHIK
SKLNTEQHHQRLAQINDEIAVIERVL
3D structure
PDB7o4o Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m 1 A22-tRNA methyltransferase TrmK.
ChainA
Resolution1.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.217: tRNA (adenine(22)-N(1))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A R7 G24 D26 V48 D75 G76 C92 G93 R8 G25 D27 V49 D76 G77 C93 G94
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0160105 tRNA (adenine(22)-N1)-methyltransferase activity
Biological Process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7o4o, PDBe:7o4o, PDBj:7o4o
PDBsum7o4o
PubMed35595101
UniProtA0A0D6HIR7

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