Structure of PDB 7nzi Chain A

Receptor sequence
>7nziA (length=207) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
PWADDFLAENADIAISNPADYKGKWNTVFGNDNPIHIEVGTGKGQFISGM
AKQNPDINYIGIELFKSVIVTAVQKVKDSEAQNVKLLNIDADTLTDVFEP
GEVKRVYLNFSDPWPKKRHEKRRLTYSHFLKKYEEVMGKGGSIHFKTDNR
GLFEYSLKSFSEYGLLLTYVSLDLHNSNLEGNIMTEYEEKFSALGQPIYR
AEVEWRT
3D structure
PDB7nzi Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.33: tRNA (guanine(46)-N(7))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A V45 G46 E69 L70 D96 A97 N115 F116 D118 T191 E192 Y193 V39 G40 E63 L64 D90 A91 N109 F110 D112 T185 E186 Y187
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008176 tRNA (guanine(46)-N7)-methyltransferase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
GO:0032259 methylation
GO:0036265 RNA (guanine-N7)-methylation
GO:0106004 tRNA (guanine-N7)-methylation
Cellular Component
GO:0043527 tRNA methyltransferase complex

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Cellular Component
External links
PDB RCSB:7nzi, PDBe:7nzi, PDBj:7nzi
PDBsum7nzi
PubMed34006170
UniProtO34522|TRMB_BACSU tRNA (guanine-N(7)-)-methyltransferase (Gene Name=trmB)

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