Structure of PDB 7nz7 Chain A

Receptor sequence
>7nz7A (length=166) Species: 10090 (Mus musculus) [Search protein sequence]
PDGPCVVSVQETEKWMEEAMRMAKEALENIEVPVGCLMVYNNEVVGKGRN
EVNQTKNATRHAEMVAIDQVLDWCHQHGQSPSTVFEHTVLYVTVEPCIMC
AAALRLMKIPLVVYGCQNERFGGCGSVLNIASADLPNTGRPFQCIPGYRA
EEAVELLKTFYKQENP
3D structure
PDB7nz7 The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination.
ChainA
Resolution2.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.33: tRNA(adenine(34)) deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H71 C107 C110 H61 C97 C100
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008251 tRNA-specific adenosine deaminase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0052717 tRNA-specific adenosine-34 deaminase activity
Biological Process
GO:0002100 tRNA wobble adenosine to inosine editing
GO:0008033 tRNA processing

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7nz7, PDBe:7nz7, PDBj:7nz7
PDBsum7nz7
PubMed34057470
UniProtQ6P6J0|ADAT2_MOUSE tRNA-specific adenosine deaminase 2 (Gene Name=Adat2)

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