Structure of PDB 7nrf Chain A

Receptor sequence
>7nrfA (length=368) Species: 83334 (Escherichia coli O157:H7) [Search protein sequence]
GSFNFGIGYGTESGVSFQAGVQQDNWLGTGYAVGINGTKNDYQTYAELSV
TNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKSYGTDVTLGFPINEYN
SLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFKTDDFTFN
YGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDD
DHKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAV
YFPHQDLSKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWDMG
TVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFK
KYDGDKAEQFQFNIGKTW
3D structure
PDB7nrf The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G424 S425 F426 N427 F428 I430 Q446 L780 K808 G1 S2 F3 N4 F5 I7 Q23 L338 K366
BS02 C8E A I621 W627 F718 I198 W204 F276
BS03 C8E A L529 G530 F570 L106 G107 F147
BS04 C8E A F572 P602 F149 P179
BS05 C8E A F426 V444 F3 V21
Gene Ontology
Biological Process
GO:0071709 membrane assembly
Cellular Component
GO:0019867 outer membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7nrf, PDBe:7nrf, PDBj:7nrf
PDBsum7nrf
PubMed33854236
UniProtP0A940|BAMA_ECOLI Outer membrane protein assembly factor BamA (Gene Name=bamA)

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