Structure of PDB 7nb7 Chain A

Receptor sequence
>7nb7A (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
SEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDG
VQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLIS
FGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF
H
3D structure
PDB7nb7 The Effect of Core Replacement on S64315, a Selective MCL-1 Inhibitor, and Its Analogues.
ChainA
Resolution2.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U6N A H224 A227 F228 M231 M250 V253 R263 T266 L267 F270 G271 H55 A58 F59 M62 M81 V84 R94 T97 L98 F101 G102
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
Biological Process
GO:0042981 regulation of apoptotic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7nb7, PDBe:7nb7, PDBj:7nb7
PDBsum7nb7
PubMed34497901
UniProtQ07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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