Structure of PDB 7na9 Chain A

Receptor sequence
>7na9A (length=434) Species: 1491 (Clostridium botulinum) [Search protein sequence]
PVTINNFNYNDPIDNNNIIMMEPPFARGTGRYYKAFKITDRIWIIPERYT
FGYKPEDFNKRDVCEYYDPDYLNTNDKKNIFLQTMIKLFNRIKSKPLGEK
LLEMIINGIPYLGDRRVPLEEFNTNIASVTVNKLISNPGEVERKKGIFAN
LIIFGPGPVLNENETIDIGIQNHFASREGFGGIMQMKFCPEYVSVFNNVQ
ENKGASIFNRRGYFSDPALILMHELIHVLHGLYGIKVDDLPIVPNEKKFF
MQSTDAIQAEELYTFGGQDPSIITPSTDKSIYDKVLQNFRGIVDRLNKVL
VCISDPNININIYKNKFKDKYKFVEDSEGKYSIDVESFDKLYKSLMFGFT
ETNIAENYKIKTRASYFSDSLPPVKIKNLLDNEIYTIEEGFNISDKDMEK
EYRGQNKAINKQAYEEISKEHLAVYKIQMCKSVK
3D structure
PDB7na9 Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies.
ChainA
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.69: bontoxilysin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H230 H234 E268 H223 H227 E261
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7na9, PDBe:7na9, PDBj:7na9
PDBsum7na9
PubMed34990480
UniProtP10844|BXB_CLOBO Botulinum neurotoxin type B (Gene Name=botB)

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