Structure of PDB 7n8w Chain A

Receptor sequence
>7n8wA (length=214) Species: 9606 (Homo sapiens) [Search protein sequence]
SKQLFDYLIVIDFESTCWNDGKHHHSQEIIEFPAVLLNTSTGQIDSEFQA
YVQPQEHPILSEFCMELTGIKQAQVDEGVPLKICLSQFCKWIHKIQQQKN
IIFATGISEPSASEVKLCAFVTWSDWDLGVCLEYECKRKQLLKPVFLNSW
IDLRATYKLFYRRKPKGLSGALQEVGIEFSGREASGLDASRNTALLAWKM
IRDGCVMKITRSLN
3D structure
PDB7n8w Crystal structure of ERI2 nuclease bound to rAMP
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A E43 S44 C46 L96 E14 S15 C17 L67
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:7n8w, PDBe:7n8w, PDBj:7n8w
PDBsum7n8w
PubMed
UniProtA8K979|ERI2_HUMAN ERI1 exoribonuclease 2 (Gene Name=ERI2)

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