Structure of PDB 7n7p Chain A

Receptor sequence
>7n7pA (length=313) Species: 9606 (Homo sapiens) [Search protein sequence]
PLGDCLRDWEDLQQDFQNIQETHRLYRLKLEELTKLQNNCTSSITRQKKR
LQELALALKKCKAQELENQMKERQGLFFDMEAYLPKKNGLYLSLVLGNVN
VTLLSKQAKFAYKDEYEKFKLYLTIILILISFTCRFLLNSRVTDAAFNFL
LVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQ
KFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHVEGFQSWMWRGL
TFLLPFLFFGHFWQLFNALTLFNLAQDPQCKEWQVLMCGFPFLLLFLGNF
FTTLRVVHHKFHS
3D structure
PDB7n7p TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase.
ChainA
Resolution3.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A K130 E179 S187 R188 I189 W193 Q237 Y240 Q241 L279 V328 K332 K113 E162 S170 R171 I172 W176 Q220 Y223 Q224 L257 V306 K310
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005216 monoatomic ion channel activity
GO:0005515 protein binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
GO:0045444 fat cell differentiation
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
GO:0051260 protein homooligomerization
GO:0051291 protein heterooligomerization
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005637 nuclear inner membrane
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7n7p, PDBe:7n7p, PDBj:7n7p
PDBsum7n7p
PubMed34374645
UniProtQ9BXJ8|TACAN_HUMAN Ion channel TACAN (Gene Name=TMEM120A)

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