Structure of PDB 7n5u Chain A

Receptor sequence
>7n5uA (length=82) Species: 9606 (Homo sapiens) [Search protein sequence]
KAFQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVH
MRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVH
3D structure
PDB7n5u Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
ChainA
Resolution2.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Q392 R399 H400 T403 R421 Y451 Q14 R21 H22 T25 R43 Y73
BS02 dna A K396 Q422 D423 K426 Y438 K18 Q44 D45 K48 Y60
BS03 ZN A C412 C415 H428 H432 C34 C37 H50 H54
BS04 ZN A C384 C387 H400 H404 C6 C9 H22 H26
BS05 ZN A C440 H456 H460 C62 H78 H82
External links
PDB RCSB:7n5u, PDBe:7n5u, PDBj:7n5u
PDBsum7n5u
PubMed36626981
UniProtO95365|ZBT7A_HUMAN Zinc finger and BTB domain-containing protein 7A (Gene Name=ZBTB7A)

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