Structure of PDB 7n43 Chain A

Receptor sequence
>7n43A (length=202) Species: 6523 (Lymnaea stagnalis) [Search protein sequence]
LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDV
VFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTP
QLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREI
SVDPTTEDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRK
KG
3D structure
PDB7n43 Unique Pharmacological Properties of alpha-Conotoxin OmIA at alpha 7 nAChRs.
ChainA
Resolution2.47 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y89 W143 T144 H145 Y185 C188 Y192 Y89 W143 T144 H145 Y182 C185 Y189
BS02 peptide A W53 Q55 Q73 R104 E110 L112 M114 T155 E157 E163 Y164 W53 Q55 Q73 R104 E110 L112 M114 T155 E157 E160 Y161
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity
GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
Biological Process
GO:0006811 monoatomic ion transport
GO:0007165 signal transduction
GO:0007268 chemical synaptic transmission
GO:0034220 monoatomic ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0050877 nervous system process
GO:0060078 regulation of postsynaptic membrane potential
GO:0060079 excitatory postsynaptic potential
Cellular Component
GO:0005576 extracellular region
GO:0016020 membrane
GO:0043005 neuron projection
GO:0043083 synaptic cleft
GO:0045202 synapse
GO:0098794 postsynapse

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7n43, PDBe:7n43, PDBj:7n43
PDBsum7n43
PubMed34955864
UniProtP58154|ACHP_LYMST Acetylcholine-binding protein

[Back to BioLiP]