Structure of PDB 7n3z Chain A

Receptor sequence
>7n3zA (length=379) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
KSENTIRFLTFNVNGIRTFFHYQPFSQMNQSLRSVFDFFRADIITFQELK
TEKLSISKWGRVDGFYSFISIPQTRKGYSGVGCWIRIPEKNHPLYHALQV
VKAEEGITGYLTIKNGKHSAISYRNDVNQGIGGYDSLDPDLDEKSALELD
SEGRCVMVELACGIVIISVYCPANSNSSEEGEMFRLRFLKVLLRRVRNLD
KIGKKIVLMGDVNVCRDLIDSADTLEQFSIPITDPMGGTKLEAQYRDKAI
QFIINPDTPHRRIFNQILADSLLPDASKRGILIDTTRLIQTRNRLKMYTV
WNMLKNLRPSNYGSRIDFILVSLKLERCIKAADILPDILGSDHCPVYSDL
DILDDRIEPGTTQVPIPKFEARYKYNLRN
3D structure
PDB7n3z Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2.
ChainA
Resolution1.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.11.2: exodeoxyribonuclease III.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A N25 E59 N14 E48
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:7n3z, PDBe:7n3z, PDBj:7n3z
PDBsum7n3z
PubMed36198268
UniProtP38207|APN2_YEAST DNA-(apurinic or apyrimidinic site) endonuclease 2 (Gene Name=APN2)

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