Structure of PDB 7n2s Chain A

Receptor sequence
>7n2sA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEYWDRETQISKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB7n2s Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
ChainA
Resolution2.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 T24 E45 E63 S67 D77 Y84 L95 Y99 D116 T143 W147 Y159 W167 Y7 T24 E45 E63 S67 D77 Y84 L95 Y99 D116 T143 W147 Y159 W167
Gene Ontology
Biological Process
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
Cellular Component
GO:0016020 membrane
GO:0030670 phagocytic vesicle membrane
GO:0042612 MHC class I protein complex
GO:0098553 lumenal side of endoplasmic reticulum membrane

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7n2s, PDBe:7n2s, PDBj:7n2s
PDBsum7n2s
PubMed36477533
UniProtA3F718

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