Structure of PDB 7n0l Chain A

Receptor sequence
>7n0lA (length=313) Species: 10090 (Mus musculus) [Search protein sequence]
LGDCLRNWEDLQQDFQGIQETHRLYRLKLEELTKLQANCTNSITRQKKRL
QELALVLKKCRPSLSMEAAQELENQMKERQGLFFDMEAYLPKKNGLYLSL
VLGNVNVTLLSKQAKFAYKDEYEKFKLYLTIILIVISFTCRFLLNSRVTD
AAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFAAYVSTFLSGVMLTWP
DGLMYQKFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRAEGFQSWMWRGL
TFLLPFLFFGHFWQLFNALTLFNLARDPECKEWQVLMCGFPFLLLFLGNF
FTTLRVVHQKFHS
3D structure
PDB7n0l Analysis of the mechanosensor channel functionality of TACAN.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A K130 S187 R188 I189 W193 F226 Q230 Y240 Q241 L279 G282 H283 K332 K119 S176 R177 I178 W182 F215 Q219 Y229 Q230 L257 G260 H261 K310
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0034220 monoatomic ion transmembrane transport
GO:0045444 fat cell differentiation
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
GO:0051260 protein homooligomerization
GO:0051291 protein heterooligomerization
Cellular Component
GO:0005634 nucleus
GO:0005637 nuclear inner membrane
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:7n0l, PDBe:7n0l, PDBj:7n0l
PDBsum7n0l
PubMed34374644
UniProtQ8C1E7|TACAN_MOUSE Ion channel TACAN (Gene Name=Tmem120a)

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