Structure of PDB 7mxh Chain A

Receptor sequence
>7mxhA (length=281) Species: 9606 (Homo sapiens) [Search protein sequence]
SEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDSESGTIIFLHQWS
KGQFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGCEL
HSGGSPEGFFQVAFNGLDLLSFQQTTWVPSPGCGSLAQSVCHLLNHQYEG
VTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSGPSPGPGRLQ
LVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANGTWYLRATLDVAD
GEAAGLSCRVKHSSLEGQDIILYWRGSLVPR
3D structure
PDB7mxh Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells.
ChainA
Resolution2.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZQ7 A V12 Q14 L69 F70 F72 Y73 F170 V8 Q10 L65 F66 F68 Y69 F166
BS02 ZP7 A G76 L77 H84 S143 L147 G72 L73 H80 S139 L143
External links
PDB RCSB:7mxh, PDBe:7mxh, PDBj:7mxh
PDBsum7mxh
PubMed34536421
UniProtP29016|CD1B_HUMAN T-cell surface glycoprotein CD1b (Gene Name=CD1B);
P29017|CD1C_HUMAN T-cell surface glycoprotein CD1c (Gene Name=CD1C)

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