Structure of PDB 7ms6 Chain A

Receptor sequence
>7ms6A (length=111) Species: 9606 (Homo sapiens) [Search protein sequence]
VRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRR
YFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSL
AEHLSHFGIDM
3D structure
PDB7ms6 Structure-Activity Relationship of USP5 Inhibitors.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZPV A W209 G220 R221 Y223 D225 Y259 Y261 M266 W37 G48 R49 Y51 D53 Y87 Y89 M94
BS02 ZN A C199 C202 C219 H232 C27 C30 C47 H60
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:7ms6, PDBe:7ms6, PDBj:7ms6
PDBsum7ms6
PubMed34648286
UniProtP45974|UBP5_HUMAN Ubiquitin carboxyl-terminal hydrolase 5 (Gene Name=USP5)

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