Structure of PDB 7ms5 Chain A

Receptor sequence
>7ms5A (length=115) Species: 9606 (Homo sapiens) [Search protein sequence]
GEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCG
RRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDP
SLAEHLSHFGIDMLK
3D structure
PDB7ms5 Structure-Activity Relationship of USP5 Inhibitors.
ChainA
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C199 C202 C219 H232 C29 C32 C49 H62
BS02 ZOG A W209 G220 R221 Y223 Y259 Y261 M266 W39 G50 R51 Y53 Y89 Y91 M96
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:7ms5, PDBe:7ms5, PDBj:7ms5
PDBsum7ms5
PubMed34648286
UniProtP45974|UBP5_HUMAN Ubiquitin carboxyl-terminal hydrolase 5 (Gene Name=USP5)

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