Structure of PDB 7mph Chain A

Receptor sequence
>7mphA (length=90) Species: 9606 (Homo sapiens) [Search protein sequence]
GPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQH
FKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIF
3D structure
PDB7mph Synthesis and structural characterization of a monocarboxylic inhibitor for GRB2 SH2 domain.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZLY A S96 Q106 H107 F108 K109 L111 L120 W121 S39 Q49 H50 F51 K52 L54 L63 W64
External links
PDB RCSB:7mph, PDBe:7mph, PDBj:7mph
PDBsum7mph
PubMed34506932
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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