Structure of PDB 7mon Chain A

Receptor sequence
>7monA (length=268) Species: 9606 (Homo sapiens) [Search protein sequence]
EQIKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKAGSIAIV
RQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRE
LLDREKDLTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGY
QVKLAGFELRKTQTSMSDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIV
LWEIATGDIPFQGCNSEKIRKLVAVKRQQEPLGEDCPSELREIIDECRAH
DPSVRPSVDEILKKLSTF
3D structure
PDB7mon Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis.
ChainA
Resolution2.23 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZL1 A R210 N212 L217 M283 C286 G289 L338 D369 R20 N22 L27 M90 C93 G96 L145 D168
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7mon, PDBe:7mon, PDBj:7mon
PDBsum7mon
PubMed34811356
UniProtQ8NB16|MLKL_HUMAN Mixed lineage kinase domain-like protein (Gene Name=MLKL)

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