Structure of PDB 7moa Chain A

Receptor sequence
>7moaA (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
KRRNTIHEFKKSAKTTLIKIDPIKTKKVNTADQCANRCTRNKGLPFTCKA
FVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSY
KGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG
PWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWD
HQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIK
TCAD
3D structure
PDB7moa Structural basis of the activation of c-MET receptor.
ChainA
Resolution4.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SGN A K62 K63 R73 K26 K27 R37
BS02 IDS A Q69 R73 Q33 R37
BS03 SGN A R35 Q69 N72 R73 R76 R2 Q33 N36 R37 R40
BS04 IDS A K34 N72 T75 R76 K1 N36 T39 R40
BS05 SGN A R36 T75 R76 R3 T39 R40
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7moa, PDBe:7moa, PDBj:7moa
PDBsum7moa
PubMed34210960
UniProtP14210|HGF_HUMAN Hepatocyte growth factor (Gene Name=HGF)

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