Structure of PDB 7mjz Chain A

Receptor sequence
>7mjzA (length=444) Species: 820 (Bacteroides uniformis) [Search protein sequence]
ADDNKKLFIETYGCQMNVADSEVIASVMQMAGYSVADTLEEADAVFMNTC
SIRDNAEQKILNRLEFFHSLKKKKRGLIVGVLGCMAERVKDDLITNHHVD
LVVGPDAYLTLPELIASVEAGEKAMNVELSTTETYRDVIPSRICGNHISG
FVSIMRGCNNFCTYCIVPYTRGRERSRDVESILNEVADLVAKGYKEVTLL
GQNVNSYRFEKPDGETITFPMLLRTVAEAAPGVRIRFTTSHPKDMSDETL
QVIADMPNVCKHIHLPVQSGSSRILKLMNRKYDREWYMDRVAAIRRIIPD
CGLSTDIFSGFHSETEEDHQLSLSLMEECGYDSAFMFKYSERPGTHASKY
LPDDVPEEVKIRRLNEIIALQNRLSAEANARCVGKTYEVLVEGVSKRSRD
QLFGRTEQNRVVVFDRGTHRVGDFVMVKVTESSSATLKGEEVAG
3D structure
PDB7mjz Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB.
ChainA
Resolution2.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.4.3: tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 A G26 C27 N30 C63 S64 I65 C97 V180 G13 C14 N17 C50 S51 I52 C84 V167
BS02 SF4 A C171 N173 C175 Y177 C178 V180 P181 Q215 C158 N160 C162 Y164 C165 V167 P168 Q202
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0035596 methylthiotransferase activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0035600 tRNA methylthiolation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mjz, PDBe:7mjz, PDBj:7mjz
PDBsum7mjz
PubMed34526715
UniProtA0A174GYG1

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