Structure of PDB 7mj2 Chain A

Receptor sequence
>7mj2A (length=208) Species: 220668 (Lactiplantibacillus plantarum WCFS1) [Search protein sequence]
NGFPEVIYGAGKTATQIVGIVQALSQQTLPILTTRLSAEKFAALQPALPT
AVYHATAQCMTVGEQPAPKTPGYIAVVTAGTSDQPVAEEAAVTAETFGNR
VERVYDVGVAGIHRLFAKLDVIRGARVVIVIAGMEGALASVVGGLVDKPV
IAVPTSVGYGTSFQGMTALLTMLNSCASGITVVNIDNGFGAAYSASMVNQ
MSHPQFEK
3D structure
PDB7mj2 The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.143: pyridinium-3,5-biscarboxylic acid mononucleotide synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A G188 V191 S223 G143 V146 S178
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006189 'de novo' IMP biosynthetic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mj2, PDBe:7mj2, PDBj:7mj2
PDBsum7mj2
PubMed34548397
UniProtF9UST0|LARB_LACPL Pyridinium-3,5-biscarboxylic acid mononucleotide synthase (Gene Name=larB)

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