Structure of PDB 7mfl Chain A

Receptor sequence
>7mflA (length=885) Species: 195103 (Clostridium perfringens ATCC 13124) [Search protein sequence]
GVEITEGVTVTAKGNTEGNTADLAIDGDLSTYWESSNDYKWIEVDLGGIY
ELSKIEIFNKDEAVYKYNIYASEDGENFNKIAYKNNDNVSDSNGNMHTID
NVRAGKIRIDVVQNSNSDRVNIAEINVFGKNTGESLPEVKKIATSNFSET
PWATEYEKFNSDSAYANEKTLNEIKNLVGRVIGREFKDKFIFEIRDQLNG
NDVFEVSDSGDGKVLIKGNNGVSLASGFNYYLKNYCNVSYNPIMGSNLKM
PETMPSVGERVVIDTPYEHRYALNFCTYSYTMSFWDWDQYEEFLDWCAMN
GVNLVLDIIGQEEVLRRTLNEFGYSDEEVKEFISGPAYFAWFYMQNMTGF
GGPLPNDWFEQRAELGRKMHDRMQSFGINPVLQGYSGMVPRDFKEKNQEA
QTISQGGWCGFDRPDMLKTYVNEGEADYFQKVADVFYEKQKEVFGDVTNF
YGVDPFHEGGNTGDLDNGKIYEIIQNKMIEHDNDAVWVIQNWQGNPSNNK
LEGLTKKDQAMVLDLFSEVSPDWNRLEERDLPWIWNMLHNFGGRMGMDAA
PEKLATEIPKALANSEHMVGIGITPEAINTNPLAYELLFDMAWTRDQINF
RTWTEDYIERRYGKTNKEILEAWNIILDTAYKKRNDYYQGAAESIINARP
GFGIKSASTWGHSKIVYDKSEFEKAIEIFAKNYDEFKDSDAFLYDFADIL
KQLLANSAQEYYEVMCNAYNNGNGEKFKFVSGKFLELIKLQERVLSTRPE
FLIGNWIEDARTMLKDSDDWTKDLFEFNARALVTTWGSRNNADGGGLKDY
SNRQWSGLTEDYYYARWEKWINGLQAELDGGAKAPNIDWFKMEYDWVNKK
SDTDKLYPTEASNENLGELAKIAMESYSVTNMDKI
3D structure
PDB7mfl Iminosugar C-Glycosides Work as Pharmacological Chaperones of NAGLU, a Glycosidase Involved in MPS IIIB Rare Disease*.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A L48 D51 D53 T56 A148 E149 L23 D26 D28 T31 A123 E124
BS02 SO4 A N492 S522 N524 N467 S497 N499
BS03 SO4 A N40 E42 G43 T45 N15 E17 G18 T20
BS04 SO4 A K214 T278 M279 K189 T253 M254
BS05 Z8V A C301 Y305 W366 H482 W517 L540 E601 Q664 Y825 C276 Y280 W341 H457 W492 L515 E576 Q639 Y800
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