Structure of PDB 7mf3 Chain A

Receptor sequence
>7mf3A (length=890) Species: 9031 (Gallus gallus) [Search protein sequence]
WSAKKLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKVTLSKDDIQKM
NPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYK
QLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGE
SGAGKTENTKKVIQYLAVVASSGELEKQLLQANPILEAFGNAKTVKNDNS
SRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIA
GASEQMRNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFT
EEEQTSILRVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINV
TDFTRSILTPRIKVGRDVVQKAQTKEQADFAIEALAKAKFERLFRWILTR
VNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLCINYTNEKLQQLFNH
TMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALLDEEC
WFPKATDTSFVEKLIQEQGNHAKFQKSKQLKDKTEFCILHYAGKVTYNAS
AWLTKNMDPLNDNVTSLLNQSSDKFVADLWKDVDRIVGLDQTKKGMFRTV
GQLYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNG
VLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKA
LELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIIAFQAQCRGYLAR
KAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEE
MQAKDEELQRTKERQQKAEAELKELEQKHTQLCEEKNLLQEKLQAETELY
AEAEEMRVRLAAKKQELEEILHEMEARIEEEEERSQQLQA
3D structure
PDB7mf3 Cryo-EM structure of the autoinhibited state of myosin-2.
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N125 P126 G180 A181 G182 K183 T184 N242 S246 N97 P98 G152 A153 G154 K155 T156 N197 S201
BS02 MG A T184 S246 T156 S201
Gene Ontology
Molecular Function
GO:0000146 microfilament motor activity
GO:0000287 magnesium ion binding
GO:0003774 cytoskeletal motor activity
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0008307 structural constituent of muscle
GO:0032027 myosin light chain binding
GO:0043531 ADP binding
GO:0045159 myosin II binding
GO:0051015 actin filament binding
Biological Process
GO:0006939 smooth muscle contraction
GO:0030239 myofibril assembly
GO:0030241 skeletal muscle myosin thick filament assembly
GO:0031032 actomyosin structure organization
GO:0048251 elastic fiber assembly
GO:0055013 cardiac muscle cell development
Cellular Component
GO:0005737 cytoplasm
GO:0005859 muscle myosin complex
GO:0016459 myosin complex
GO:0016460 myosin II complex
GO:0030016 myofibril
GO:0032982 myosin filament

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mf3, PDBe:7mf3, PDBj:7mf3
PDBsum7mf3
PubMed34936462
UniProtP10587|MYH11_CHICK Myosin-11 (Gene Name=MYH11)

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