Structure of PDB 7m9p Chain A
Receptor sequence
>7m9pA (length=99) Species:
11676
(Human immunodeficiency virus 1) [
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PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGI
GGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNVIGRNLLTQIGCTLNF
3D structure
PDB
7m9p
HIV-1 Protease in Complex with ligands
Chain
A
Resolution
1.819 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
2.7.7.-
2.7.7.49
: RNA-directed DNA polymerase.
2.7.7.7
: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2
: exoribonuclease H.
3.1.26.13
: retroviral ribonuclease H.
3.4.23.16
: HIV-1 retropepsin.
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
YWS
A
D25 G27 A28 D29 G48 G49 I50 G52 F53 V82
D25 G27 A28 D29 G48 G49 I50 G52 F53 V82
Gene Ontology
Molecular Function
GO:0004190
aspartic-type endopeptidase activity
Biological Process
GO:0006508
proteolysis
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:7m9p
,
PDBe:7m9p
,
PDBj:7m9p
PDBsum
7m9p
PubMed
UniProt
P12497
|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)
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