Structure of PDB 7m7v Chain A

Receptor sequence
>7m7vA (length=267) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
GFVRTLRARPEAGGKVPVFVFHPAGGSTVVYEPLLGRLPADTPMYGFERV
EGSIEERAQQYVPKLIEMQGDGPYVLVGWSLGGVLAYACAIGLRRLGKDV
RFVGLIDAVRAGEEIPQTKEEIRKRWDRYAAFAEKTFNPAIPYEQLEELD
DEGQVRFVLDAVSQSIPAGIIEHQRTSYLDNRAIDTAQIQPYDGHVTLYM
ADRYHDDAIMFEPRYAVRQPDGGWGEYVSDLEVVPIGGEHIQAIDEPIIA
KVGEHMSRALGQIEADR
3D structure
PDB7m7v Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target.
ChainA
Resolution2.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 Z3J A Y1582 S1636 Y1637 N1640 D1644 Y1663 F1670 Y1674 Y129 S177 Y178 N181 D185 Y204 F211 Y215
Gene Ontology
Biological Process
GO:0009058 biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:7m7v, PDBe:7m7v, PDBj:7m7v
PDBsum7m7v
PubMed34910486
UniProtI6X8D2|PKS13_MYCTU Polyketide synthase Pks13 (Gene Name=pks13)

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