Structure of PDB 7m5w Chain A

Receptor sequence
>7m5wA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
DHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQ
KYHDLAFQVKEAHFKAHPDWKWCNPYSSLRRTLDQRRALVMQLFQDHGFF
PSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAA
3D structure
PDB7m5w Molecular basis of DNA recognition by the HMG-box-C1 module of Capicua
ChainA
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R35 R36 M38 M42 K46 R49 D60 N61 R62 L126 R130 K169 R4 R5 M7 M11 K15 R18 D29 N30 R31 L83 R87 K126
BS02 dna A N39 F41 R62 S65 W72 Y73 W103 R171 R174 Q175 N8 F10 R31 S34 W41 Y42 W72 R128 R131 Q132
External links
PDB RCSB:7m5w, PDBe:7m5w, PDBj:7m5w
PDBsum7m5w
PubMed
UniProtQ96RK0|CIC_HUMAN Protein capicua homolog (Gene Name=CIC)

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