Structure of PDB 7m4n Chain A

Receptor sequence
>7m4nA (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
AEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGANRMSCRCGAQMCY
LCRVSINGYDHFCQHPRSPGAPCQECSRCSLWTDPTEDDEKLIEEIQKEA
EEEQKRKNGENFKRIGPPLE
3D structure
PDB7m4n Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216.
ChainA
Resolution2.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C675 C693 C695 C24 C42 C44
BS02 ZN A C700 C703 H712 C730 C49 C52 H61 C79
BS03 ZN A C714 H716 C724 C727 C63 H65 C73 C76
External links
PDB RCSB:7m4n, PDBe:7m4n, PDBj:7m4n
PDBsum7m4n
PubMed34998453
UniProtQ9NWF9|RN216_HUMAN E3 ubiquitin-protein ligase RNF216 (Gene Name=RNF216)

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