Structure of PDB 7m3z Chain A

Receptor sequence
>7m3zA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPVFECGNVVLRTD
ERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGIMNDE
KFNLKLVIK
3D structure
PDB7m3z Fragment-Based Discovery of Small Molecules Bound to T-Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3).
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 YQD A D53 V54 W57 S59 Y61 W62 L63 D53 V54 W57 S59 Y61 W62 L63
BS02 CA A I93 G95 N98 D99 I93 G95 N98 D99
External links
PDB RCSB:7m3z, PDBe:7m3z, PDBj:7m3z
PDBsum7m3z
PubMed34597046
UniProtQ8TDQ0|HAVR2_HUMAN Hepatitis A virus cellular receptor 2 (Gene Name=HAVCR2)

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