Structure of PDB 7m10 Chain A

Receptor sequence
>7m10A (length=68) Species: 9606 (Homo sapiens) [Search protein sequence]
TVPVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPN
CEKTHGKSTLKKKRTWHK
3D structure
PDB7m10 Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions.
ChainA
Resolution1.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 Y14 V16 T17 F19 M20 I21 E22 W29 E39 Y48 Y5 Y12 V14 T15 F17 M18 I19 E20 W27 E37 Y46
BS02 ZN A C23 C26 C50 C53 C21 C24 C48 C51
BS03 ZN A C8 C10 H31 C34 C6 C8 H29 C32
Gene Ontology
Cellular Component
GO:0048188 Set1C/COMPASS complex

View graph for
Cellular Component
External links
PDB RCSB:7m10, PDBe:7m10, PDBj:7m10
PDBsum7m10
PubMed33969871
UniProtO75151|PHF2_HUMAN Lysine-specific demethylase PHF2 (Gene Name=PHF2)

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