Structure of PDB 7lzs Chain A

Receptor sequence
>7lzsA (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
SQIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGL
FYSIFTDQLKRNLSVINLDPEINPEGFNILLDFMYTSRLNLREGNIMAVM
ATAMYLQMEHVVDTCRKFIKAS
3D structure
PDB7lzs Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor.
ChainA
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 YJS A H14 N21 R24 L25 H8 N15 R18 L19
External links
PDB RCSB:7lzs, PDBe:7lzs, PDBj:7lzs
PDBsum7lzs
PubMed36793435
UniProtP41182|BCL6_HUMAN B-cell lymphoma 6 protein (Gene Name=BCL6)

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