Structure of PDB 7lxi Chain A

Receptor sequence
>7lxiA (length=279) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
LRPFYEESQSIYDVSDEFFSLFLDPTMAYTCAYFEREDMTLEEAQNAKFD
LALDKLHLEPGMTLLDIGCGWGGGLQRAIENYDVNVIGITLSRNQFEYSK
AKLAKIPTERSVQVRLQGWDEFTDKVDRIVSIGAFEAFKMERYAAFFERS
YDILPDDGRMLLHTILTYTQKQMHEMGVKVTMSDVRFMKFIGEEIQLPAQ
EDIFKFAQAADFSVEKVQLLQQHYARTLNIWAANLEANKDRAIALQSEEI
YNKYMHYLTGCEHFFRKGISNVGQFTLTK
3D structure
PDB7lxi Crystal structure of S-adenosylmethionine-dependent methyltransferase UmaA from Mycobacterium tuberculosis in complex with SAH
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A T33 G71 G73 T93 L94 Q98 G121 W122 I135 F141 T30 G68 G70 T90 L91 Q95 G118 W119 I132 F138
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0008610 lipid biosynthetic process
GO:0032259 methylation
GO:0071768 mycolic acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7lxi, PDBe:7lxi, PDBj:7lxi
PDBsum7lxi
PubMed
UniProtQ6MX39|UMAA_MYCTU S-adenosylmethionine-dependent methyltransferase UmaA (Gene Name=umaA)

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