Structure of PDB 7lrk Chain A

Receptor sequence
>7lrkA (length=119) Species: 9606 (Homo sapiens) [Search protein sequence]
TEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGV
IKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCA
EVLESFFVQKLKGFKASRS
3D structure
PDB7lrk Pyridazone inhibitors of BPTF bromodomain
ChainA
Resolution1.44 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YC4 A P2951 F2952 V2956 D2960 Y3006 N3007 F3013 P34 F35 V39 D43 Y89 N90 F96
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016589 NURF complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7lrk, PDBe:7lrk, PDBj:7lrk
PDBsum7lrk
PubMed34515477
UniProtQ12830|BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF (Gene Name=BPTF)

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