Structure of PDB 7lpk Chain A

Receptor sequence
>7lpkA (length=119) Species: 9606 (Homo sapiens) [Search protein sequence]
STEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYG
VIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQC
AEVLESFFVQKLKGFKASR
3D structure
PDB7lpk Pyridazone inhibitors of BPTF bromodomain
ChainA
Resolution1.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 Y9P A P2951 F2952 Y3006 N3007 F3013 P35 F36 Y90 N91 F97
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016589 NURF complex

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Biological Process

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Cellular Component
External links
PDB RCSB:7lpk, PDBe:7lpk, PDBj:7lpk
PDBsum7lpk
PubMed34515477
UniProtQ12830|BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF (Gene Name=BPTF)

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